Monday, April 23, 2012

Lipid Metabolism



How would you explain the connection between glucose entering the body and energy created by the body to a friend, using your new biochemistry knowledge?


Overall, there are a set of specific chemical reactions that take place in the human body to sustain life, for example, the pathway of glycolysis. Glycolysis, in anaerobic conditions, produces lactic acid as its final product, which can cause plaque and bacteria build up in the mouth of humans etc. The body can tell what it will use for nutritious purposes and what is toxic to the body. There are many crucial steps in chemical reactions that take place in the body. Enzymes can be considered the main component of most metabolic pathways. Enzymes allow humans/organisms to catalyze reactions efficiently that require energy and would not occur by themselves, for example, by spontaneous reactions or by coupling reactions, which release energy.

For example, Ingested fat is taken in through the mouth, to the stomach, and into the small intestine, where it is broken down by bile. Long chain fatty acids are packed together in the small intestine and are taken up by the mucosal cells in the small intestine to be used for the synthesis of chylomicrons (composed of cholesterol, phospholipids, triacyglygerols, and apoproteins). Chylomicrons can then enter into the blood and be dispersed throughout the body for "fuel". This fuel helps the body’s cells to function properly and grow efficiently. This process of lipid metabolism and enzyme regulation of metabolic pathways also allows humans to be able to reproduce, respond to changes in the cells environment and/or receive signals from other cells in the body.

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